The Luz Station was built in the late nineteenth century to host the São Paulo Railway Company, of British origin, and was for many years the main entrance to the city of Sao Paulo. The railway line ran from Santos and its seaport on the state's coast, where coffee was exported, up to Jundiaí, in the countryside. From there goods, merchandises and imported capital came to supply the city.

Today the station is part of the transport network of the Companhia Paulista de Trens Metropolitanos, with a free transfer to the Estação Luz do Metro de São Paulo.

Characteristic contrasts of the city are visible in the region of the station: while important cultural sites like Jardim da Luz, Pinacoteca do Estado, Museu de Arte Sacra, Museu da Lingua Portuguesa and Sala Sao Paulo attracts intellectuals, artists and tourists, the close proximity of Cracolândia (Crack cocaine land) brings misery and intricate social problems, which culminated in the violent Cracolândia Operation, an action conducted by the military police in 2012 to combat drug trafficking in the region and to assist crack cocaine addicteds.
Inspired by this adverse and odd environment, the Boca do Lixo Movement, birthplace of the marginal cinema in Brazil, was formed there in the late 1960s.

As a traditional point of arrival of immigrants to the city, the Luz Station is mentioned in songs from northeaster artists who settled in São Paulo, like Tom Zé and Raul Seixas.